Acute cardiac care & resuscitationCohort study

Short and long-term outcomes among patients with and without psychiatric disorders following out-of-hospital cardiac arrest

Heart RhythmPublished

  • Registry-based cohort study
  • multiple logistic regression
  • Utstein-defined subgroups

Authors' conclusion

Pre-existing psychiatric disorders are associated with lower odds of 30-day OHCA survival, primarily because of unfavorable pre-hospital factors, including limited bystander intervention.

Study context

Population
Adult patients with non-traumatic OHCA in the British Columbia Cardiac Arrest registry (2009–2016)OHCAs, 4438 (46%) had a pre-existing psychiatric disorder
Participants
9,173 patients
Exposure
patients with psychiatric disorders compared with patients without psychiatric disorders
  • Psychiatric disordersn = 4,438

Main finding

As reported in the abstract

Pre-hospital OHCA characteristics
Psychiatric disorders vs Without psychiatric disordersOR
OHCA in public locations
0.64(95% CI 0.57–0.73)
witnessed OHCA
0.75(CI 0.69–0.82)
bystander cardiopulmonary resuscitation
0.86(CI 0.79–0.95)
bystander applied AED
0.56(CI 0.41–0.77)
initial shockable rhythm
0.54(CI 0.49–0.61)

Observational data: associations, not effects.

Further findings

OutcomeOR (CI)
30-day post-OHCA survival0.72 (0.63–0.82)
30-day survival, Utstein subgroups · 30 days — Psychiatric disorders vs Without psychiatric disorders1.04 (0.79–1.34)
30-day survival, Utstein subgroups · 30 days — Psychiatric disorders vs Without psychiatric disorders0.89 (0.70–1.13)
  • 30-day survival, Utstein subgroups: bystander-witnessed OHCA who received cardiopulmonary resuscitation
  • 30-day survival, Utstein subgroups: initial shockable rhythm who achieved return of spontaneous circulation upon hospital arrival

30-day survival, Utstein subgroups

we did not detect an association between psychiatric disorders and 30-day survival

Original publication

Short and long-term outcomes among patients with and without psychiatric disorders following out-of-hospital cardiac arrest. Heart Rhythm. Published 5 May 2026. doi:10.1016/j.hrthm.2026.04.057

Summarised from the published abstract; every number is checked against it