Arrhythmias & electrophysiologyRandomised controlled trial
Short-duration head-up tilt test potentiated with sublingual nitroglycerin in suspected vasovagal syncope: the fast Italian protocol
- Randomised controlled trial
- non-inferiority
Authors' conclusion
The diagnostic value of the Fast HUTT protocol is similar to that of the Traditional protocol and therefore the Fast protocol can be used instead of the Traditional protocol.
Study context
- Population
- Consecutive patients undergoing head-up tilt test (HUTT) for suspected vasovagal syncope
- Participants
- 554 patients
- Comparison
- Fast vs Traditional nitroglycerin (NTG)-potentiated HUTT protocol
- Fastn = 277
- Traditionaln = 277reference
- Primary endpoint
- Positivity rate (induction of syncope in presence of hypotension/bradycardia)
Primary result
As reported in the abstract
Positive response
Further findings
Vasodepressor response
- Vasodepressor response — Trend of lesser vasodepressor response with Fast, significant during the passive phase
- P = 0.01
Original publication
Short-duration head-up tilt test potentiated with sublingual nitroglycerin in suspected vasovagal syncope: the fast Italian protocol. Eur Heart J. Published 2 June 2023. doi:10.1093/eurheartj/ehad322
Summarised from the published abstract; every number is checked against it