Heart failure & cardiomyopathies

Short-term outcomes of pediatric HeartMate 3 left ventricular assist device: single center experience

ESC Heart FailPublished retrospective cohort study

Authors' conclusion

HM3 LVADs have favourable safety profiles and survival outcomes in paediatric patients with end-stage heart failure. These findings support HM3’s as a viable option for managing advanced heart failure in the Saudi paediatric population, with further studies warranted to assess long-term outcomes.

Study context

Population
Paediatric patients treated with HeartMate 3 (HM3) VAD, 2022 to 2024, Saudi Arabiaconsecutive paediatric patients treated with HM3
Participants
15 patients
Outcome
In-hospital mortality
Methodological detailssingle tertiary cardiac centre, consecutive patients
  • Single tertiary cardiac centre
  • Consecutive patients

Main finding

As reported in the abstract

In-hospital mortality, patients
two

Observational data: associations, not effects.

Further findings

Transplantation · median follow-up 17 months

Successful transplantation
60% (n = 9)

Survival · 1 year

Overall 1-year survival
87%
1-year transplantation-free survival rate
55%
No mortality beyond hospital discharge

Baseline characteristics

Mean age (years)
11.07
Females
67%
Average body surface area
1.2 m² (range 0.85-1.76 m²)
Dilated cardiomyopathy
n = 13, 87%

Length of stay

Days

Median ICU stay
42
Median hospital stay
56

Follow-up

Median follow-up period
17 months

Safety

Complications

Strokes
n = 2, 13%
Re-exploration for bleeding
n = 1, 7%
Driveline infection
n = 2, 14%
Device thrombosis
n = 1, 7%

Original publication

Short-term outcomes of pediatric HeartMate 3 left ventricular assist device: single center experience. ESC Heart Fail. Published 8 January 2026. doi:10.1093/eschf/xvaf017

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