Simplification of continuous intracoronary thermodilution
Authors' conclusion
Predicting Ti resulted in an excellent agreement with measured Ti for the assessment of coronary blood flow.
Study context
- Population
- Patients with continuous intracoronary thermodilution Q measurementcohorts of 371, 120 and 23
- Comparison
- Simplified Q vs standard Q and positron emission tomography (PET)-derived Q
- PET-derived Qn = 23reference
- Outcome
- Agreement of simplified Q (predicted saline entry temperature Ti) with standard Q and PET-derived Q
Methodological detailsderivation and validation cohorts, Ti prediction equation derived by multivariate linear regression in 371 patients with Q at rest and hyperaemia
- Derivation and validation cohorts
- Ti prediction equation derived by multivariate linear regression in 371 patients with Q at rest and hyperaemia
Performance
As reported in the abstract
Agreement of simplified Q
- Simplified Q vs Standard Q · validation cohort of 120
- r 0.94 (CI 0.93–0.95); P < 0.001
- Simplified Q vs Standard Q · validation cohort of 120
- ICC 0.94 (CI 0.92–0.95); P < 0.001
- Simplified Q vs PET-derived Q · validation cohort of 23
- r 0.86 (CI 0.75–0.92); P < 0.001
- Simplified Q vs PET-derived Q · validation cohort of 23
- ICC 0.84 (CI 0.72–0.91); P < 0.001
- No significant difference vs standard Q in correlation coefficients with PET-derived Q
- P = 0.29
- No significant difference vs standard Q in SDs of absolute differences with PET-derived Q
- P = 0.85
Original publication
Simplification of continuous intracoronary thermodilution. EuroIntervention. Published 7 October 2024. doi:10.
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