Congenital heart disease

Single-Ventricle Outcomes After Neonatal Palliation of Severe Ebstein Anomaly With Modified Starnes Procedure

CirculationPublished Retrospective cohort study

Authors' conclusion

Long-term single-ventricle outcomes among neonatal survivors of the modified Starnes procedure are excellent.

Study context

Population
Neonates with severe Ebstein anomaly undergoing Starnes procedure, 1989–2015
Participants
27 vs 24
Exposure
Entire vs Fenestrated RV exclusion
  • Entiren = 27
  • Fenestrated RV exclusionn = 24
Outcome
Long-term single-ventricle outcomes (survival)
Follow-up
1, 5 and 10 years

Main finding

As reported in the abstract

Survival · 1, 5, and 10 years
Group1 year5 years10 years
Entire81±4%81±5%76±3%
Fenestrated RV exclusion87±2%87±2%81±4%

1 year

Entire81±4%
Fenestrated RV exclusion87±2%

5 years

Entire81±5%
Fenestrated RV exclusion87±2%

10 years

Entire76±3%
Fenestrated RV exclusion81±4%

Observational data: associations, not effects.

Further findings

Early mortality (same hospitalization), by RV exclusion type

Nonfenestrated RV exclusion (3 patients): died
2 (67%)
Remaining 24 patients: died during the same hospitalization
3 (13%)

Single-ventricle course of the 22 neonatal survivors · follow-up 7 (6-8) years

Fontan completion
20
Awaiting Glenn procedure
1
Died after Glenn procedure
1
Indexed pulmonary vascular resistance
1.8 (1.2-2.3) W/m²
Mean pulmonary pressure
12 (9-18) mm Hg
Pacemaker implantation
2

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Single-Ventricle Outcomes After Neonatal Palliation of Severe Ebstein Anomaly With Modified Starnes Procedure. Circulation. Published 25 October 2016. doi:10.1161/circulationaha.115.021241

Summarised from the published abstract; every number is checked against it

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