Heart failure & cardiomyopathiesCohort study
Socioeconomic Disadvantage, John Henryism, and Incident Heart Failure in the Jackson Heart Study
- cohort
Authors' conclusion
The association between income disadvantage and HF differed by JH level. Because SED and high JH tend to co-occur, both should be considered in future research aiming to decrease the burden of HF in Black Americans.
Study context
- Population
- Black adults from the Jackson, Mississippi Metropolitan area with no cardiovascular disease at baseline (2000–2004) with complete socioeconomic disadvantages (SED) and John Henryism (JH) scoresmean age: 52.15 years, 64.3% female, 100 heart failure (HF) events occurred by 2016
- Participants
- 1,704 adults
- Exposure
- Effect moderation of JH in the SED and incident HF association
Main finding
As reported in the abstract
Incident HF · by 2016 (mean follow-up, 10 years)
HF events
100
Observational data: associations, not effects.
Further findings
| Outcome | hazard ratio (95% CI) | |
|---|---|---|
| Incident HF per 1-unit increase in income disadvantage score, high JH · among those with high JH; after full adjustment | 2.00 (1.39–2.86) | |
| Incident HF per 1-unit increase in income disadvantage score, low JH — per 1-unit increase in income disadvantage score · among participants with low JH; unadjusted | 1.40 (1.04–1.90) | |
| Incident HF per 1-unit increase in income disadvantage score, low JH — per 1-unit increase in income disadvantage score | 1.19 (0.87–1.63) | |
| 0.20.5125Hazard ratio (log scale) |
- Incident HF per 1-unit increase in income disadvantage score, low JH: among participants with low JH; after adjusting for age and sex
Interaction between income and JH for incident HF
- statistically significant interaction
- P = 0.04
Original publication
Socioeconomic Disadvantage, John Henryism, and Incident Heart Failure in the Jackson Heart Study. Circ Popul Health Outcomes. Published 17 March 2026. doi:10.1161/circoutcomes.125.012740
Summarised from the published abstract; every number is checked against it