Coronary disease & ACSSecondary analysis
Socioeconomic status, cardiovascular risk factors and coronary atherosclerosis: a SCOT-HEART trial analysis
- Secondary analysis of the SCOT-HEART randomised trial
- post-hoc analysis
- multicentre
Authors' conclusion
Socioeconomic status is not an independent predictor of coronary artery disease severity, rather, the association is mostly determined by modifiable risk factors. Preventive therapies, guided by CCTA, achieves similar benefits in both low and high socioeconomic status individuals.
Study context
- Population
- SCOT-HEART participants with socioeconomic status available; plaque analysis in those randomised to coronary computed tomography angiography (CCTA)1,629 scans analysed
- Participants
- 3,948 participants
- Comparison
- Low vs high socioeconomic status
- Primary endpoint
- Association of socioeconomic status with qualitative and quantitative CCTA plaque features; interaction of socioeconomic status on CV outcomes
Primary result
As reported in the abstract
Quantitative plaque burden
Further findings
CCTA-guided management: changes in medical therapy and CHD death or non-fatal MI, low vs high socioeconomic groups · median 4.75 years
- Similar changes in medical therapy and similar risk reductions in low and high socioeconomic groups; no difference between base and interaction models
- P = 0.35
Original publication
Socioeconomic status, cardiovascular risk factors and coronary atherosclerosis: a SCOT-HEART trial analysis. Eur J Prev Cardiol. Published 5 March 2025. doi:10.1093/eurjpc/zwaf121
Summarised from the published abstract; every number is checked against it