Arrhythmias & electrophysiology
Spatial association between CT-derived myocardial deformation and stereotactic radioablation targets in ventricular tachycardia: Insights from the RAVENTA trial
Authors' conclusion
CT-derived ED-ES radial deformation abnormalities show a substantial spatial association with clinically defined STAR targets, alongside partial discordance, and may complement substrate characterisation in patients undergoing STAR.
Study context
- Population
- Patients with ventricular tachycardia undergoing stereotactic arrhythmia radioablation (STAR)patients undergoing STAR
- Participants
- 9 patients
- Comparison
- CT-derived end-diastolic-end-systolic (ED-ES) radial deformation abnormalities vs clinically defined STAR targets (transferred from voltage maps)
- Outcome
- Discrimination of target-positive segments (segment level)
Methodological detailsinsights from the RAVENTA trial
- Insights from the RAVENTA trial
Main finding
As reported in the abstract
- Radial deformation AUC
- 0.80; 95% CI 0.73-0.88
- Longitudinal deformation AUC
- 0.71; 95% CI 0.66-0.76
- Radial vs longitudinal, DeLong
- P < .001
Further findings
Abnormal radial deformation by segment target status
Centroid distance between abnormal regions and STAR targets
- Median centroid distance
- 20.4 mm (IQR, 15.4-33.7)
Mean surface distance
- Median mean surface distance
- 6.0 mm (IQR, 2.8-9.7)
Volumetric overlap
- Deformation-defined regions with partial volumetric overlap
- 9 of 11
- STAR targets overlapping with at least 1 deformation-defined abnormality
- 10 of 11
Regions identified
- Abnormal radial deformation regions
- Eleven
- STAR targets
- 11
Original publication
Spatial association between CT-derived myocardial deformation and stereotactic radioablation targets in ventricular tachycardia: Insights from the RAVENTA trial. Heart Rhythm. Published 28 August 2026. doi:10.
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