Spontaneous coronary artery dissection outcomes among pregnant vs. non-pregnant women
Authors' conclusion
Among hospitalized patient, P-SCAD was associated with similar clinical outcomes and reduced incidence of death when compared with NP-SCAD, though had higher rates of 30-day readmission.
Study context
- Population
- Hospitalized women with Spontaneous Coronary Artery Dissection (SCAD), National Readmission Database, January 2016 to December 2020
- Exposure
- Pregnancy-associated SCAD vs non-pregnant SCAD
- Outcome
- Death
Methodological detailspropensity-score matched, national database, Greedy 1:1 propensity matching; multivariate logistic and Cox regression
- Propensity-score matched
- National database
- Greedy 1:1 propensity matching; multivariate logistic and Cox regression
Main finding
As reported in the abstract
P-SCAD vs NP-SCADOdds ratio (CI)P value
Propensity matched
0.11(0.02–0.61)
P = 0.012- Non-propensity matched
- OR 0.21 (CI 0.3–1.54); P = 0.123
Observational data: associations, not effects.
Further findings
| Outcome | P-SCAD | NP-SCAD | OR (CI) | P value | |
|---|---|---|---|---|---|
| Readmission · 30 daysNon-propensity matched | 15.8% | 11.2% | 1.68 (1.24–2.29) | P = 0.001 | |
| Readmission · 30 daysPropensity matched | 3.39 (1.93–5.97) | P < 0.001 | |||
| 0.20.5125Odds ratio (log scale) |
Original publication
Spontaneous coronary artery dissection outcomes among pregnant vs. non-pregnant women. Eur Heart J Acute Cardiovasc Care. Published 17 April 2024. doi:10.
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