Coronary disease & ACSTrial design
Staged interventional strategies for acute ST-segment elevation myocardial infarction patient with multivessel disease: Rationale and design of a multicenter, randomized STAGED trial
- investigator-initiated, multicenter, randomized study
- 37 sites
Study context
- Population
- Acute STEMI patients with multivessel disease (MVD) undergoing successful primary percutaneous coronary intervention (PCI) of the culprit lesion followed by staged complete revascularization (SCR)planned enrolment (aiming to include)
- Participants
- 1,586 patients
- Planned comparison
- timing of SCR: early-staged PCI and delayed-staged PCI
- Primary endpoint
- major adverse cardiac event (MACE), including cardiovascular death, myocardial infarction, or ischemia-driven revascularization for both culprit and nonculprit vessels
- Follow-up
- 12 months since the randomization
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Staged interventional strategies for acute ST-segment elevation myocardial infarction patient with multivessel disease: Rationale and design of a multicenter, randomized STAGED trial. Am Heart J. Published 13 January 2026. doi:10.1016/j.ahj.2026.107352
Summarised from the published abstract; every number is checked against it