Coronary disease & ACSSecondary analysis
Standardised versus visual assessment of device success after percutaneous coronary intervention
- prespecified analysis of the Multivessel TALENT trial
- lesion-level substudy
- core lab adjudication
Authors' conclusion
In this prespecified lesion-level substudy, standardised assessment using the EAPCI device success algorithm with core lab QCA reclassified a substantial proportion of operator-adjudicated successes and identified lesions at higher 1-year LOCE risk. (ClinicalTrials.gov: NCT04390672).
Study context
- Population
- Patients with three-vessel disease randomised to treatment with either Supraflex Cruz or SYNERGY stentspatients, percutaneous coronary intervention (PCI) attempted in 4,052 lesions
- Participants
- 1,548 patients
- Comparison
- visually evaluated device success by the operator at the end of percutaneous coronary intervention (PCI) aligns with the European Association of Percutaneous Cardiovascular Interventions (EAPCI)-endorsed standardised definition adjudicated by the core lab
Primary result
As reported in the abstract
Device success · end of PCI
Further findings
LOCE by QCA-based device success · 1 year
- Lesion-oriented composite endpoint (LOCE) by quantitative coronary angiography (QCA)-based device success: log-rank p=0.041
Device success and LOCE by stent
- Device success and LOCE rates did not differ between the two stents for any definition
Original publication
Standardised versus visual assessment of device success after percutaneous coronary intervention. EuroIntervention. Published 5 October 2026. doi:10.4244/eij-d-26-00413
Summarised from the published abstract; every number is checked against it