Heart failure & cardiomyopathiesCohort study
Stratifying prognosis in heart failure patients with reduced ejection fraction and atrial cardiomyopathy
- registry cohort
- linked to the territory-wide Clinical Data Analysis and Reporting System
Authors' conclusion
High FIND-AF risk is associated with adverse prognosis in a cohort of patients with HFrEF and AtCM but without baseline AF. These exploratory data require external validation and a prospective study.
Study context
- Population
- Patients with heart failure with reduced ejection fraction (HFrEF) and atrial cardiomyopathy (AtCM) without AF at baseline, ECG-HF registry (2010–6)
- Participants
- 164 patients
- Exposure
- High vs low FIND-AF risk
- high-riskn = 32
- low-riskn = 132reference
- Outcome
- Composite of:
- Incident AF
- Ischaemic stroke
- All-cause mortality
- Follow-up
- Followed until 31 December 2019
Main finding
As reported in the abstract
high-risk vs low-riskEstimate (95% CI)P value
Composite of incident AF, ischaemic stroke, and all-cause mortality
OR 2.48(1.07–5.76)
P = 0.035model including both FIND-AF risk group and AtCM severity
adjusted OR 2.70(1.14–6.40)
P = 0.024Observational data: associations, not effects.
Further findings
Discrimination, FIND-AF vs CHA2DS2-VASc
- Composite outcome AUC FIND-AF vs CHA2DS2-VASc
- .735 vs .641; DeLong P = .007
- Ischaemic stroke AUC FIND-AF vs CHA2DS2-VASc
- .700 vs .575; DeLong P = .008
Original publication
Stratifying prognosis in heart failure patients with reduced ejection fraction and atrial cardiomyopathy. ESC Heart Fail. Published 21 May 2026. doi:10.1093/eschf/xvag144
Summarised from the published abstract; every number is checked against it