Stress-Induced Autonomic Dysfunction is Associated With Mental Stress–Induced Myocardial Ischemia in Patients With Coronary Artery Disease
Authors' conclusion
In individuals with coronary artery disease, mental stress-induced autonomic dysfunction may be a mechanism implicated in the causal pathway of MSIMI.
Study context
- Population
- Patients with stable CAD undergoing a standardized laboratory speech stressor with Holter monitoring
- Participants
- 735 patients
- Exposure
- Low heart rate variability (HRV) vs high HRV during mental stress
- Outcome
- Mental stress-induced myocardial ischemia (MSIMI)
Main finding
As reported in the abstract
MSIMI, by HRV during stress
Low HRV vs High HRVOdds ratio (95% CI)
High-frequency HRV during stress
2.1(1.3–3.3)
Low-frequency HRV during stress
2.1(1.3–3.3)
Observational data: associations, not effects.
Further findings
- Low-frequency HRV at rest also associated with mental stress-induced myocardial ischemia (MSIMI), with slightly reduced effect estimates
Original publication
Stress-Induced Autonomic Dysfunction is Associated With Mental Stress–Induced Myocardial Ischemia in Patients With Coronary Artery Disease. Circ Cardiovasc Imaging. Published 13 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →