Coronary disease & ACSCohort study
Stress Perfusion Cardiac Magnetic Resonance (CMR) Imaging-Guided Management and Prognosis in Patients With Suspected Coronary Heart Disease
- observational study
- all consecutive patients
- 3 centers in France
Authors' conclusion
In this registry of consecutive patients with chronic coronary syndrome from 3 centers, stress CMR-guided revascularization was associated with a lower rate of death. The combined assessment of inducible myocardial ischemia and LGE may help to select patients most suitable for revascularization.
Study context
- Population
- Patients who underwent stress CMR for suspected or known chronic coronary syndromepatients included, 1:1 propensity-matched cohort of 1700 patients
- Participants
- 50,701 patients
- Exposure
- CMR-guided coronary revascularization vs no CMR-guided revascularization
- Outcome
- All-cause death
- Follow-up
- Median 7.2 years (interquartile range, 3.0-11.0)
Main finding
As reported in the abstract
CMR-guided revascularizationAdjusted hazard ratio (99.5% CI)P value
overall population
0.30(0.25–0.36)
1:1 propensity-matched cohort of 1700 patients
0.37(0.28–0.50)
P < 0.001- patients died
- 3665 (7.2%)
Observational data: associations, not effects.
Further findings
Predictors of death: ischemia and late gadolinium enhancement (LGE) without viability
| Comparison | adjusted hazard ratio (99.5% CI) | P value | |
|---|---|---|---|
| Ischemia | 3.67 (3.15–4.27) | P < 0.001 | |
| LGE without viability | 1.26 (1.10–1.44) | P < 0.001 | |
| 0.20.5125Adjusted hazard ratio (log scale) |
Revascularization among patients with ischemia
- of the 7396 patients with ischemia, underwent revascularization
- 6523 (88%)
Effect of CMR-guided revascularization by LGE status (subgroup)
- patients without LGE or with LGE and viability: beneficial effect
- P < 0.001 for both
- patients with LGE without viability: no beneficial effect
- P = 0.23
Original publication
Stress Perfusion CMR Imaging-Guided Management and Prognosis in Patients With Suspected Coronary Heart Disease. Circ Cardiovasc Interv. Published 29 January 2026. doi:10.1161/circinterventions.125.015765
Summarised from the published abstract; every number is checked against it