Valvular & structural heart diseaseCohort study
Stroke Risk After Transcatheter Aortic Valve Replacement (TAVR)
- Registry analysis (Society of Thoracic Surgeons (STS)/American College of Cardiology Transcatheter Valve Therapy Registry)
- inverse probability of treatment weighting
- weighted time-to-event models
- CommonSpirit Health hospitals
Authors' conclusion
In this registry of patients receiving TAVR, valve type did not predict stroke at 1 year. The predominant drivers of stroke were clinical variables: age, STS risk, and a history of stroke.
Study context
- Population
- Patients who underwent TAVR across CommonSpirit Health hospitals from January 2021 to February 2023patients who underwent TAVR during the study period · balloon-expandable valve 5,445 · self-expanding valves (SEV) 1,218
- Participants
- 6,663 patients
- Exposure
- association between valve type and the risk of stroke within 1 year after contemporary TAVR
- balloon-expandable valven = 5,445
- SEVn = 1,218
- Outcome
- Stroke-free survival
- Follow-up
- 1 year
Main finding
As reported in the abstract
Adjusted hazard ratio
1.54
95% CI 0.79–2.68
P = 0.294
valve type
adjusted HR 1.54 (95% CI 0.79–2.68); P = 0.294
Observational data: associations, not effects.
Further findings
Female sex (baseline) · more females received a SEV
P < 0.001
| Outcome | balloon-expandable valve | SEV | P value |
|---|---|---|---|
| STS risk score (baseline) · higher in the SEV group | mean 4.0 ± 3.5 | mean 4.5 ± 3.8 | P < 0.001 |
Stroke · within the study period
- patients who experienced stroke
- 87 (1.3%)
Predictors of stroke
- Age, lower body mass index, prior stroke, STS risk, and alternative access were associated with stroke
Original publication
Stroke Risk After TAVR. JACC Adv. Published 9 April 2026. doi:10.1016/j.jacadv.2026.102727
Summarised from the published abstract; every number is checked against it