Arrhythmias & electrophysiologyTrial design
Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design
- multicenter, double-blinded, randomized trial
- randomized in a 1:1 fashion
- rationale and design
Study context
- Population
- Patients admitted to an intensive care unit with electrical storm (ES)planned enrolment (will be randomized)
- Participants
- 192 patients
- Planned comparison
- dexmedetomidine to placebo in the acute treatment of patients with ES
- Primary endpoint
- composite of:
- All-cause in-hospital mortality
- Recurrent ventricular arrhythmia prompting intervention
- Follow-up
- Duration of hospitalization
No results yet. This paper sets out the design of a trial; its results are to come.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design. Am Heart J. Published 25 January 2026. doi:10.1016/j.ahj.2026.107358
Summarised from the published abstract; every number is checked against it