Subclinical congestion assessed by lung ultrasound in ST segment elevation myocardial infarction
Main findingResult — go to the resultAdjusted relative risk 6.0 95% CI 2.3–16.2Authors' conclusion
Early subclinical pulmonary congestion identified by LUS in patients with Killip I STEMI at hospital admission is associated with adverse outcomes during hospitalisation and 30-day follow-up.
Study context
- Population
- Patients admitted for segment elevation myocardial infarction (STEMI) without signs of heart failure (HF) at admission; Lung ultrasound (LUS) within 24 hours after revascularisation
- Participants
- 312 patients
- Exposure
- Wet lung vs dry lung on LUS
- Outcome
- Composite of:
- Acute HF
- Cardiogenic shock
- Death
- Follow-up
- During hospitalisation
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Adjusted relative risk
6.0
95% CI 2.3–16.2
P = 0.007
Events by group
Wet lungvs Dry lung
adjusted RR 6.0 (95% CI 2.3–16.2); P = 0.007
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Wet lung | Dry lung | Adjusted HR (95% CI) | P value | |
|---|---|---|---|---|---|
| Composite of readmission for HF, new ACS or death · 30-day follow-up | 11.6% | 1.2% | 5.4 (1.0–28.7) | P = 0.049 | |
| 0.050.21520Adjusted hazard ratio (log scale) |
Addition of LUS to Zwolle score for follow-up composite endpoint
- Net reclassification improvement
- 0.99
NPV of LUS
- NPV for in-hospital endpoint
- 97.4%
- NPV for follow-up endpoint
- 98.9%
Original publication
Subclinical congestion assessed by lung ultrasound in ST segment elevation myocardial infarction. Heart. Published 2 June 2023. doi:10. 1136/ heartjnl-2023-322690
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