Cardio-oncology & otherCohort study
Survival following aortic valve surgery for prosthetic valve endocarditis: a SWEDEHEART study
- population-based observational cohort study
Authors' conclusion
While PVE patients had higher short-term mortality, patients who survived 30 days after surgery had a similar 10-year prognosis to NVE patients. These results are encouraging and suggest that good long-term outcomes are achievable after surgery for PVE.
Study context
- Population
- All patients receiving aortic valve surgery for endocarditis in Sweden (1997–2022)Prosthetic valve endocarditis (PVE) 685 (26%) · native valve endocarditis (NVE) 1,900 (74%)
- Participants
- 2,585 patients
- Exposure
- comparing PVE and native valve endocarditis
- PVEn = 685
- NVEn = 1,900reference
Main finding
30-day mortality · 30 days
Adjusted odds ratio
1.76
95% CI 1.20–2.59
By group
PVE vs NVE
adjusted OR 1.76 (95% CI 1.20–2.59)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | absolute survival difference (95% CI) | |
|---|---|---|
| Long-term survival among patients who lived past 30 days after surgery · 10 years · Long-term survival was similar for PVE and NVE | −4.6% (−10.4 to 1.5) | |
| −15−10−505Difference (linear scale) |
years
| Outcome | PVE | NVE | Estimate |
|---|---|---|---|
| Age | 68 | 61 |
Age
- PVE patients had more comorbidities than NVE patients
Follow-up
years
- Mean follow-up
- 7.1
- maximum
- 26
Original publication
Survival following aortic valve surgery for prosthetic valve endocarditis: a SWEDEHEART study. Heart. Published 30 July 2026. doi:10.1136/heartjnl-2026-327973
Summarised from the published abstract; every number is checked against it