Arrhythmias & electrophysiologyResearch article
Symptom-Triggered 6-Lead Electrocardiographic (ECG) Monitoring Significantly Increases Arrhythmia Detection Beyond Traditional Ambulatory Monitoring
- comparative effectiveness study
Authors' conclusion
These findings demonstrate that patient-initiated, symptom-triggered ECG monitoring substantially enhances arrhythmia detection compared with traditional short-duration monitoring.
Study context
- Population
- Patients with palpitations or other arrhythmic symptoms referred for standard ambulatory monitoring (24- or 48-hour Holter or ambulatory ECG patch)enrolled, 6,251 KM6L recordings (median 15 per patient) · 24/48-hour Holter 140
- Participants
- 350 patients
- Comparison
- Detection rates between KM6L and standard monitoring
Main finding
As reported in the abstract
Significant arrhythmias detected using either ambulatory ECG monitoring or KM6L
Patients with significant arrhythmias
66 patients (18.9%)
Further findings
Arrhythmia detection · McNemar test
- Arrhythmia detection: P < 0.001
Arrhythmia episodes detected exclusively by KM6L
- Detected exclusively by KM6L
- 39 arrhythmia episodes (11.1%)
- P
- P = 0.0008
- Most commonly atrial fibrillation
- n = 23
Original publication
Symptom-Triggered 6-Lead ECG Monitoring Significantly Increases Arrhythmia Detection Beyond Traditional Ambulatory Monitoring. JACC Adv. Published 19 August 2026. doi:10.1016/j.jacadv.2026.103102
Summarised from the published abstract; every number is checked against it