A Systematic Review of “Food Is Medicine” Randomized Controlled Trials for Noncommunicable Disease in the United States: A Scientific Statement From the American Heart Association
Methodological detailssystematic review of randomised controlled trials
- Systematic review of randomised controlled trials
Recommendations
As issued by the authors
14 RCTs identified; more than one-third early-stage smaller-scale (stage 1) trials
Broad variation in populations, intervention design, duration, intensity and outcomes precluded many direct comparisons
Food Is Medicine approaches often positively influence diet quality and food security, consistent with observational literature
Impact on clinical outcomes inconsistent and often not statistically significant
Need for larger, higher-quality studies measuring clinical outcomes and additional RCTs mapping program type to health outcomes
Original publication
A Systematic Review of “Food Is Medicine” Randomized Controlled Trials for Noncommunicable Disease in the United States: A Scientific Statement From the American Heart Association. Circulation. Published 18 June 2025. doi:10.
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