Cardio-oncology & otherCross-sectional study
Systemic inflammation, myocardial fibrosis, and subclinical cardiovascular disease in people living with HIV
- cross-sectional pilot study
- matched
Authors' conclusion
Limited data from this pilot study suggest that HIV may be associated with increased cardiac fibrosis and decreased right ventricular function. This study highlights the need for larger longitudinal studies to better understand the trajectory of HIV-associated cardiac changes and help improve cardiac disease prevention in this population.
Study context
- Population
- Veterans with and without HIV receiving care at the Providence VA Medical Centerveterans with HIV 21 · controls 20
- Participants
- 21 vs 20
- Exposure
- matched veterans with and without HIV
- veterans with HIVn = 21
- controlsn = 20
Main finding
As reported in the abstract
GDF-15 blood levels, extracellular volume, right heart function on MRI
- higher growth differentiation factor (GDF)-15 blood levels, increased extracellular volume, and lower right heart function on MRI among patients with HIV
Observational data: associations, not effects.
Original publication
Systemic inflammation, myocardial fibrosis, and subclinical cardiovascular disease in people living with HIV. Am Heart J. Published 4 March 2026. doi:10.1016/j.ahj.2026.107399
Summarised from the published abstract; every number is checked against it