Cohort study
Systolic Blood Pressure and Survival to Very Old Age: Results From the Women’s Health Initiative
- Prospective cohort study
Authors' conclusion
For women >65 years of age with low cardiovascular disease and other chronic disease risk, an SBP level <130 mm Hg was found to be associated with longevity.
Study context
- Population
- Women ≥65 years in the Women's Health Initiative without history of CVD, DM or cancer
- Participants
- 16,570 women
- Exposure
- Systolic blood pressure (SBP) levels and survival to 90 years
- Outcome
- Survival to 90 years of age
- Follow-up
- Median 19.8 years
Main finding
As reported in the abstract
Absolute probability of surviving to 90 years with SBP 110–130 mm Hg, by attained age
- Overall survival to 90 years
- 9723 of 16 570 women (59%)
- SBP 110–130 mm Hg, attained age 65 years
- 38% (95% CI, 34%-48%)
- SBP 110–130 mm Hg, attained age 70 years
- 54% (52%-56%)
- SBP 110–130 mm Hg, attained age 75 years
- 66% (64%-67%)
- SBP 110–130 mm Hg, attained age 80 years
- 75% (73%-78%)
Observational data: associations, not effects.
Further findings
Survival to 90 years by time in therapeutic range (SBP 110–130 mm Hg), attained age 80 years
- 0% time in range
- 66% (64%-69%)
- 20% time in range
- 68% (67%-70%)
- 40% time in range
- 71% (69%-72%)
- 60% time in range
- 73% (71%-74%)
- 80% time in range
- 75% (72%-77%)
- 100% time in range
- 77% (74%-79%)
Original publication
Systolic Blood Pressure and Survival to Very Old Age: Results From the Women’s Health Initiative. Circulation. Published 16 April 2024. doi:10.1161/circulationaha.123.067302
Summarised from the published abstract; every number is checked against it