Pulmonary vascular disease & thromboembolism
Tricuspid-annular-plane-systolic-excursion (TAPSE)/Systolic Pulmonary Artery Pressure (sPAP) Ratio Associated with Increased Mortality in Subjects With and Without Cardiovascular Comorbidities- Insights from a Tertiary Center Database
Authors' conclusion
Excess mortality in consecutive subjects performing echocardiography in a tertiary center is seen at higher TAPSE/sPAP values than previously described. The TAPSE/sPAP cutoff associated with excess mortality is influenced by comorbidities and hospitalization status.
Study context
- Population
- Consecutive subjects, with and without cardiovascular comorbidities, undergoing echocardiography in a single tertiary center between 2011–2021subjects included in the analysis (47% females, median age: 71 y/o, IQR: 58–81)
- Participants
- 17,951 subjects
- Exposure
- TAPSE/sPAP ratio <0.68 mm/mmHg and mortality
Methodological detailsconsecutive subjects, single tertiary center
- Consecutive subjects
- Single tertiary center
Main finding
As reported in the abstract
TAPSE/sPAP threshold associated with excess mortality
TAPSE/sPAP ratio associated with excess mortality
<0.68 mm/mmHg
Observational data: associations, not effects.
Further findings
TAPSE/sPAP threshold associated with excess mortality, by cardiovascular comorbidities (sub-group)
- With cardiovascular comorbidities
- <0.53 mm/mmHg
- Without cardiovascular comorbidities
- <0.79 mm/mmHg
Mortality with TAPSE/sPAP ratio <0.68 mm/mmHg (multivariate model)
- Adjusted hazard ratio
- 1.52, 95% confidence interval 1.42-1.63; p < 0.001
- Adjusted for baseline and echocardiographic parameters
Median TAPSE and sPAP
- Median TAPSE
- 21 mm (IQR: 18-25)
- Median sPAP
- 31 mmHg (IQR: 26-41)
Original publication
TAPSE/sPAP Ratio Associated with Increased Mortality in Subjects With and Without Cardiovascular Comorbidities- Insights from a Tertiary Center Database. Eur Heart J Cardiovasc Imaging. Published 28 September 2026. doi:10.
Summarised from the published abstract; every number is checked against it