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Pulmonary vascular disease & thromboembolismCohort study

Tricuspid-annular-plane-systolic-excursion (TAPSE)/Systolic Pulmonary Artery Pressure (sPAP) Ratio Associated with Increased Mortality in Subjects With and Without Cardiovascular Comorbidities- Insights from a Tertiary Center Database

Eur Heart J Cardiovasc ImagingPublished

  • retrospective analysis
  • consecutive subjects
  • single tertiary center
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Authors' conclusion

Excess mortality in consecutive subjects performing echocardiography in a tertiary center is seen at higher TAPSE/sPAP values than previously described. The TAPSE/sPAP cutoff associated with excess mortality is influenced by comorbidities and hospitalization status.

Study context

Population
Consecutive subjects, with and without cardiovascular comorbidities, undergoing echocardiography in a single tertiary center between 2011–2021subjects included in the analysis (47% females, median age: 71 y/o, IQR: 58–81)
Participants
17,951 subjects
Exposure
TAPSE/sPAP ratio <0.68 mm/mmHg and mortality

Main finding

As reported in the abstract

TAPSE/sPAP threshold associated with excess mortality

TAPSE/sPAP ratio associated with excess mortality

<0.68 mm/mmHg

Observational data: associations, not effects.

Further findings

TAPSE/sPAP threshold associated with excess mortality, by cardiovascular comorbidities (sub-group)

With cardiovascular comorbidities
<0.53 mm/mmHg
Without cardiovascular comorbidities
<0.79 mm/mmHg

Mortality with TAPSE/sPAP ratio <0.68 mm/mmHg (multivariate model)

adjusted hazard ratio
1.52, 95% confidence interval 1.42-1.63; p < 0.001
  • adjusted for baseline and echocardiographic parameters

Median TAPSE and sPAP

Median TAPSE
21 mm (IQR: 18-25)
Median sPAP
31 mmHg (IQR: 26-41)

Original publication

TAPSE/sPAP Ratio Associated with Increased Mortality in Subjects With and Without Cardiovascular Comorbidities- Insights from a Tertiary Center Database. Eur Heart J Cardiovasc Imaging. Published 28 September 2026. doi:10.1093/ehjci/jeag275
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Summarised from the published abstract; every number is checked against it