Targets for treatment and optimal strategies for managing hypertension in 2025: indications for clinical practice from recent hypertension guidelines
Authors' conclusion
Knowledge gaps remain regarding optimal BP thresholds and targets across sex, age, and ethnic groups.
Study context
- Population
- Recent hypertension guidelines
- Comparison
- ACC/AHA vs European Society of Cardiology (ESC) vs ESH/ISH hypertension guidelines
- Outcome
- Similarities and differences among ACC/AHA, ESC and ESH/ISH hypertension guideline recommendations
Methodological detailscomparison of guidelines
- Comparison of guidelines
Main finding
As reported in the abstract
- All guidelines trend towards earlier intervention and more stringent blood pressure (BP) targets, particularly at high CV risk
- Aligned on lifestyle recommendations and combination therapy with target BP <130/80 mmHg if risk sufficiently high and treatment well tolerated
- Differences in treatment thresholds and BP targets for elderly individuals and in classification of hypertension phenotypes in younger patients
- All endorse ACEi, ARB, calcium channel blockers and thiazide-type diuretics as first-line therapy
Original publication
Targets for treatment and optimal strategies for managing hypertension in 2025: indications for clinical practice from recent hypertension guidelines. Eur J Prev Cardiol. Published 23 September 2025. doi:10.
Summarised from the published abstract; every number is checked against it