Arrhythmias & electrophysiology
Telemonitoring-based feedback improves adherence to non-vitamin K antagonist oral anticoagulants intake in patients with atrial fibrillation
An erratum to this article was published (Eur Heart J, 1 Feb 2019 ↗)
Authors' conclusion
Telemonitoring resulted in high NOAC adherence due to the notion of being watched, as evidenced by the rapid decline during the observation period. Feedback further optimized adherence.
Study context
- Population
- Atrial fibrillation (AF) patients on OD or BID NOACcrossover
- Participants
- 48 patients
- Comparison
- Telemonitoring with immediate telephone feedback vs telemonitoring only vs observation without daily transmissions
- Primary endpoint
- Adherence to NOAC intake (taking and regimen adherence), tracked by Medication Event Monitoring System
- Follow-up
- 3 phases of 3 months each
Methodological detailssingle-blind, crossover
- Single-blind
- Crossover
Primary result
As reported in the abstract
Taking adherence
P < 0.001
| Outcome | Telemonitoring-only | Feedback | Observation | P value |
|---|---|---|---|---|
| Regimen adherence | 93.8% | 96.8% | — not stated in the abstract | P = 0.002 |
— not stated in the abstract
- Observation vs Telemonitoring-only: P = 0.049 — significant waning of taking adherence
Further findings
Persistence over entire study
- Persistence
- 98%
Adherence by NOAC regimen (OD vs BID)
- Taking adherence significantly higher for OD vs BID NOAC; unprotected days similar
Cost-effectiveness of feedback
- Incremental cost to prevent one stroke
- €344 289
- Incremental cost in high-risk patients with low adherence and optimized technology
- €15 488
Original publication
Telemonitoring-based feedback improves adherence to non-vitamin K antagonist oral anticoagulants intake in patients with atrial fibrillation. Eur Heart J. Published 2 January 2018. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →