Acute cardiac care & resuscitationCohort study

Temporal Patterns in Out-of-Hospital Cardiac Arrest Incidence and Outcome

JAMA CardiolPublished

  • Retrospective cohort study

Authors' conclusion

Results suggest that the overall OHCA incidence did not change over time, although there were differential temporal patterns among clinical subgroups. Survival improved over time overall and according to presenting rhythm, corresponding to favorable trends in community responder, prehospital, and hospital care.

Study context

Population
Adults with OHCA treated by emergency medical services (EMS), King County, Washington, 2001–2020
Participants
25,118 adults · 30,884,504 person-years
Exposure
Temporal trends 2001–2020
Outcome
Annual OHCA incidence per 100 000 person-years (AAC %) and survival to hospital discharge

Main finding

As reported in the abstract

Overall incidence per 100 000 person-years
81.3
Overall incidence 2001 vs 2020 per 100 000 person-years
88.7 vs 82.1
Overall incidence average annualized change (AAC)
−0.5% (−0.9% to 0%) (95% CI)
Overall survival to hospital discharge
17.7%
Survival to discharge 2001-2005
14.7% (859 of 5847)
Survival to discharge 2006-2010
17.4% (1024 of 5885)
Survival to discharge 2011-2015
19.3% (1232 of 6376)
Survival to discharge 2016-2020
18.9% (1322 of 7010)
Survival trend
P < .001

Observational data: associations, not effects.

Further findings

Incidence by initial rhythm

Shockable incidence per 100 000 person-years
20.9
Nonshockable incidence per 100 000 person-years
59.8
Shockable 2001 vs 2020
28.6 vs 17.9
Shockable AAC
−2.3% (−2.9% to −1.5%) (95% CI)
Nonshockable 2001 vs 2020
59.8 vs 63.7
Nonshockable AAC
0.3% (−0.1% to 0.8%) (95% CI)

Survival to discharge by rhythm, 2001-2005 vs 2016-2020

Shockable
35% (591 of 1689) vs 47.5% (768 of 1617)
Nonshockable
6.4% (265 of 4135) vs 10.1% (536 of 5323)
Trend
P < 0.001

Prehospital resuscitation (survival to hospital admission) and in-hospital survival

Temporal improvement
P < 0.001

Bystander CPR and early AED by non-EMS personnel, 2001-2005 vs 2016-2020

Bystander cardiopulmonary resuscitation
55.5% vs 73.9%
Early automated external defibrillator application by non-EMS personnel
2.2% vs 10.9%
Trend
P < 0.001

Original publication

Temporal Patterns in Out-of-Hospital Cardiac Arrest Incidence and Outcome. JAMA Cardiol. Published 1 September 2025. doi:10.1001/jamacardio.2025.2247

Summarised from the published abstract; every number is checked against it