Prevention & lipidsSecondary analysis
Temporal trend and attributable risk factors of cardiovascular disease burden for adults 55 years and older in 204 countries/territories from 1990 to 2021: an analysis for the Global Burden of Disease Study 2021
- Secondary analysis of the Global Burden of Disease Study 2021
- 204 countries and territories
Authors' conclusion
While age-standardized rates of CVD incidence, DALY, and mortality have declined over the past three decades, the total burden of CVDs continues to rise due to population ageing and growth.
Study context
- Population
- Adults aged 55 and older, 204 countries and territories, 1990–2021204 countries and territories
- Primary endpoint
- Trends in age-standardized incidence, DALY and mortality rates of overall and type-specific cardiovascular diseases (CVDs)
- Follow-up
- 1990 to 2021
Primary result
As reported in the abstract
Global age-standardized CVD rates, estimated annual percentage change · 1990–2021
Incidence, EAPC
−0.39
DALY, EAPC
−1.30
Mortality, EAPC
−1.11
Further findings
Regional, sex and age disparities
- High-middle socio-demographic index (SDI) regions: highest incidence and mortality rates; high SDI regions: greatest declines
- Men had higher age-standardized CVD incidence, DALY and mortality rates than women
- Burden increased with age; highest rates at 80+ years
Attributable risk factors
- High SBP leading modifiable risk factor, more than half of CVD-related DALY globally
- Other major risk factors: high LDL-C, smoking, ambient particulate matter pollution
Original publication
Temporal trend and attributable risk factors of cardiovascular disease burden for adults 55 years and older in 204 countries/territories from 1990 to 2021: an analysis for the Global Burden of Disease Study 2021. Eur J Prev Cardiol. Published 26 November 2024. doi:10.1093/eurjpc/zwae384
Summarised from the published abstract; every number is checked against it