Acute cardiac care & resuscitationCohort study
Temporal trends in treatment and outcomes of patients with cardiac arrest due to pulmonary embolism: a nationwide inpatient database study
- nationwide inpatient database study
- retrospectively analyzed
- 2012 and 2024
- Japan
Authors' conclusion
From 2012 to 2024, TL use decreased, whereas ECMO use increased. The survival and neurological outcomes improved over time, particularly in patients with hospital-acquired PE and those who received ECMO.
Study context
- Population
- Patients with pulmonary embolism (PE) who underwent cardiopulmonary resuscitation, nationwide inpatient database in Japanpatients with PE who underwent cardiopulmonary resuscitation
- Participants
- 10,390 patients
- Exposure
- Temporal trends in treatment patterns and outcomes
- Outcome
- Co-primary: survival to hospital discharge and favorable neurological outcomes at discharge
- Follow-up
- At discharge
Main finding
As reported in the abstract
Overall survival to hospital discharge
22.5%
Overall favorable neurological outcomes at discharge
18.5%
Observational data: associations, not effects.
Further findings
Patient characteristics
- Median patient age
- 74 years
- Men
- 44.4%
Treatment use overall
- Extracorporeal membrane oxygenation (ECMO)
- 18.4%
- TL
- 11.1%
Temporal trends in treatment · 2012 to 2023
- TL use decreased
- 16.0% to 6.7% (p < 0.001)
- ECMO use increased
- 16.0% to 20.8% (p = 0.015)
Trend subgroup analyses of survival and neurological outcomes
- Improvements particularly evident in patients with hospital-acquired PE and those treated with ECMO
Original publication
Temporal trends in treatment and outcomes of patients with cardiac arrest due to pulmonary embolism: a nationwide inpatient database study. Resuscitation. Published 8 June 2026. doi:10.1016/j.resuscitation.2026.111167
Summarised from the published abstract; every number is checked against it