Acute cardiac care & resuscitation
Temporalis muscle thickness correlates with premorbid frailty in patients resuscitated from cardiac arrest
Authors' conclusion
We found that TMT exhibits a moderate negative correlation with the CFS, supporting TMT as a tool to measure frailty. Measuring TMT in patients with early head CTs after resuscitation from cardiac arrest may allow for characterization of sarcopenia as a dimension of pre-arrest frailty.
Study context
- Population
- Adults resuscitated from cardiac arrest who had a head computed tomography (CT) obtained within 48 h of collapsesubjects enrolled
- Participants
- 50 adults
- Exposure
- Temporalis muscle thickness (TMT), measured on head CT, vs Clinical Frailty Scale
- Outcome
- CFS and TMT (descriptive)
Methodological detailsblinded investigators measured TMT
- Blinded investigators measured TMT
Main finding
As reported in the abstract
Median Clinical Frailty Scale (CFS)
4
IQR 2–6
Median TMT
6.6 [IQR 5.0-8.9] mm
Observational data: associations, not effects.
Further findings
Correlation between TMT and CFS
- Spearman ρ (moderate, negative correlation)
- −0.52
- p
- P < 0.001
Variance in CFS explained (linear regression)
- TMT R2
- 25%
- Age R2
- 17%
Original publication
Temporalis muscle thickness correlates with premorbid frailty in patients resuscitated from cardiac arrest. Resuscitation. Published 12 March 2025. doi:10. 1016/ j. resuscitation. 2025. 110578
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