Ten-year all-cause death after percutaneous or surgical revascularization in diabetic patients with complex coronary artery disease
Primary result · All-cause death in diabeticsResult — go to the resultDifference 1.9% 95% CI −7.6% to 11.1%Authors' conclusion
The treatment effects of PCI vs. CABG on all-cause death at 10 years in patients with 3VD and/or LMCAD were similar irrespective of the presence of diabetes.
Study context
- Population
- Patients with three-vessel disease and/or left main CAD, with or without diabetes452 diabetics
- Participants
- 1,800 patients
- Comparison
- Percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG), by diabetic status
- Primary endpoint
- All-cause death
- Follow-up
- 10 years
Methodological details10-year extended follow-up (SYNTAXES)
- 10-year extended follow-up (SYNTAXES)
Primary result
All-cause death in diabetics
Difference
1.9%
95% CI −7.6% to 11.1%
P = 0.551
By group
PCI vs CABG
difference 1.9% (95% CI −7.6% to 11.1%); P = 0.551
As reported in the abstract
Further findings
| Outcome | PCI | CABG | HR (95% CI) | P value | |
|---|---|---|---|---|---|
| All-cause death in diabetics · 5 years | 19.6% | 13.3% | 1.53 (0.96–2.43) | P = 0.075 | |
| All-cause death in diabetics · between 5 and 10 years | 20.8% | 24.4% | 0.82 (0.52–1.27) | P = 0.366 | |
| 0.512Hazard ratio (log scale) |
| Outcome | PCI | CABG | Difference (95% CI) | P value | |
|---|---|---|---|---|---|
| All-cause death in insulin-treated patients (subgroup, n = 182) · 10 years | 47.9% | 39.6% | 8.2% (−6.5% to 22.5%) | P = 0.227 | |
| −100102030Difference (linear scale) |
Original publication
Ten-year all-cause death after percutaneous or surgical revascularization in diabetic patients with complex coronary artery disease. Eur Heart J. Published 18 August 2021. doi:10.
Summarised from the published abstract; every number is checked against it