Coronary disease & ACSResearch article
Ten-year prognostic impact of cardiac magnetic resonance endpoints in patients with ST-segment elevation myocardial infarction
- Adjusted Cox regression models
Authors' conclusion
Smaller IS, smaller transmurality, higher MSI, and higher LVEF measured acutely and 3 months after STEMI were independently associated with lower all-cause mortality and/or hospitalization for heart failure within 10 years after STEMI, whereas MVO was not.
Study context
- Population
- Patients with STEMI who had cardiac magnetic resonance (CMR) performed during admission and/or after 3 monthspatients with either acute or follow-up CMR performed
- Participants
- 811 patients
- Comparison
- Association between CMR endpoints (IS, myocardial salvage index (MSI), left ventricular ejection fraction (LVEF), microvascular obstruction (MVO), transmurality) and all-cause mortality or hospitalization for heart failure
Main finding
As reported in the abstract
All-cause mortality or hospitalization for heart failure · median follow-up of 10.9 years
patients died or were hospitalized for heart failure
173 (21%)
Further findings
CMR endpoints as predictors of the composite outcome · 10 years after STEMI
| Comparison | adjusted HR (95% CI) | P value | |
|---|---|---|---|
| Acute IS | 1.02 (1.01–1.04) | P = 0.005 | |
| 3-month IS | 1.04 (1.02–1.06) | P < 0.001 | |
| acute MSI | 0.99 (0.98–1.00) | P = 0.007 | |
| 3-month MSI | 0.99 (0.98–1.00) | P = 0.004 | |
| acute LVEF | 0.97 (0.95–0.99) | P = 0.001 | |
| 3-month LVEF | 0.95 (0.93–0.97) | P < 0.001 | |
| acute transmurality | 1.01 (1.00–1.02) | P = 0.024 | |
| 3-month transmurality | 1.01 (1.00–1.02) | P = 0.003 | |
| MVO · MVO was not associated with the composite outcome | 1.04 (0.98–1.09) | P = 0.20 | |
| 0.512Adjusted hazard ratio (log scale) |
Original publication
Ten-year prognostic impact of cardiac magnetic resonance endpoints in patients with ST-segment elevation myocardial infarction. Eur Heart J Cardiovasc Imaging. Published 6 January 2026. doi:10.1093/ehjci/jeag001
Summarised from the published abstract; every number is checked against it