Prevention & lipidsMeta-analysis
The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis
- Systematic review and meta-analysis of cohort studies
- random-effects model
- dose-response analysis
Authors' conclusion
This meta-analysis demonstrates a significant inverse association between daily step count and all-cause mortality and CV mortality with more the better over the cut-off point of 3867 steps/day for all-cause mortality and only 2337 steps for CV mortality.
Study context
- Population
- Generally healthy individuals or patients at cardiovascular (CV) risk
- Participants
- 226,889 individuals · 17 cohort studies
- Comparison
- Higher vs lower daily step count
- Outcome
- All-cause mortality and CV mortality
- Follow-up
- Median 7.1 years
Pooled result
As reported in the abstract
All-cause and CV mortality
Each group vs referenceHazard ratio (95% CI)P value
1000-step incrementall-cause mortality; 15% decreased risk
0.85(0.81–0.91)
P < 0.001500-step incrementCV mortality; 7% decrease
0.93(0.91–0.95)
P < 0.001- All-cause mortality, lower risk vs reference quartile: Q1 / Q2 / Q3
- 48, 55, and 67%; P < 0.05, for all
- CV mortality, reduced risk vs lowest quartile: Q1 / Q2 / Q3
- 16, 49, and 77%; P < 0.05, for all
Further pooled results
Dose-response (restricted cubic splines)
- Nonlinear dose-response association between step count and all-cause and CV mortality, progressively lower risk with increased step count
- Pnonlineraly < 0.001, for both
Original publication
The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis. Eur J Prev Cardiol. Published 9 August 2023. doi:10.1093/eurjpc/zwad229
Summarised from the published abstract; every number is checked against it