Heart failure & cardiomyopathies
The Association of Echocardiographically Measured Donor Left Ventricular Mass and 1-Year Outcomes After Heart Transplantation
Authors' conclusion
Measuring donor LVM with the use of echocardiography may provide a more accurate method for donor-recipient heart size matching that could improve heart transplant outcomes, especially in obese recipients.
Study context
- Population
- Heart transplants from brain-dead donors with echocardiograms
- Participants
- 2,015 heart transplants
- Comparison
- Measured left ventricular mass (LVM) ratio vs ideally matched
- Primary endpoint
- Composite of:
- Death
- Retransplantation
- Follow-up
- 1 year
Methodological detailsmulticentre, observational
- Multicentre
- Observational
Primary result
As reported in the abstract
1-year death or retransplantation
Each group vs ideally matchedAdjusted hazard ratio (95% CI)
Undersized47% higher risk
1.47(1.01–2.15)
Oversized58% increased risk
1.58(1.05–2.37)
Further findings
Predicted heart mass (PHM) and predicted LVM ratios
- Not associated with the primary outcome
Prediction in obese recipients
- Measured LVM ratio had superior predictive power for poor post-transplant outcomes in obese recipients
Original publication
The Association of Echocardiographically Measured Donor Left Ventricular Mass and 1-Year Outcomes After Heart Transplantation. JACC Heart Fail. Published 20 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →