Congenital heart diseaseCross-sectional study
The Burden of Cardiovascular Disease in China
- Cross-sectional study
- national population-based surveillance
- 400 districts across 31 provinces
Authors' conclusion
This study revealed a substantial incident burden of CVD in China. Elevated incidence rates were particularly observed among male and elderly subgroups, with significant geographic disparities and seasonal variations in incidence.
Study context
- Population
- Adults ≥18 years with incident cardiovascular diseases (CVD) events (CHD and stroke), China CVD Surveillance Systemincident CVD events, 262 sites
- Participants
- 944,984 adults
- Outcome
- CVD incidence rate (crude and age-standardized: WSR, CSR)
- Follow-up
- 2023
Main finding
As reported in the abstract
CVD incidence
- Crude CVD incidence rate
- 620.33 per 100,000
- Age-standardized CVD incidence (WSR)
- 526.24
- Age-standardized CVD incidence (CSR)
- 635.81
- Stroke crude incidence
- 490.96 per 100,000
- CHD crude incidence
- 129.38 per 100,000
- Stroke / CHD WSR
- 416.11 and 110.14 per 100,000
- Stroke / CHD CSR
- 513.28 and 137.16 per 100,000
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Crude CVD incidence, rural vs urban · 719.38 vs 550.60 per 100,000 | P < 0.001 |
CVD incidence by sex
- Men significantly higher incidence of CVD and subtypes than females, except subarachnoid hemorrhage
- all P < 0.001
CVD incidence by age
- Age-dependent increase, particularly pronounced for ages ≥55 years
- P for trend = 0.011
Crude CVD incidence by region
- Western China
- 639.68/100,000
- Central China
- 630.18/100,000
- Eastern China
- 612.25/100,000
- Age-standardized rates elevated in eastern and central regions
- all P < 0.001
CVD incidence by calendar month
- Peak from January to March
Original publication
The Burden of Cardiovascular Disease in China. J Am Coll Cardiol. Published 8 October 2025. doi:10.1016/j.jacc.2025.08.060
Summarised from the published abstract; every number is checked against it