Acute cardiac care & resuscitation

The cost-effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest: A systematic review

ResuscitationPublished Systematic review of economic evaluations

Authors' conclusion

ECPR may be cost-effective in some settings, but there is marked variability in the reported cost-effectiveness of ECPR across current studies.

Study context

Population
Adults with refractory cardiac arrest
Participants
15 studies
Comparison
ECPR vs standard care
Outcome
Cost-effectiveness of ECPR

Pooled result

As reported in the abstract

Cost-effectiveness of ECPR across studies
High probability of ECPR being cost-effective
12 (80 %)
Low probability
1 (7 %)
Potentially cost-effective
1 (7 %)
No probability of cost-effectiveness (acute aortic dissection study)
1 (7 %)
Adjusted incremental cost-effectiveness ratios (ICERs) ranged
$2,564 to $276,307
Cost-effective at US willingness to pay threshold ($150,000)
10 studies
Cost-effective at alternative thresholds ($40,000)
7 studies

Original publication

The cost-effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest: A systematic review. Resuscitation. Published 16 September 2025. doi:10.1016/j.resuscitation.2025.110822

Summarised from the published abstract; every number is checked against it

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