The Effect of Teleprehabilitation on Adverse Events After Elective Cardiac Surgery: A Randomized Controlled Trial
Authors' conclusion
Multimodal personalized teleprehabilitation resulted in a clinically relevant and statistically significant reduction of the primary endpoint in patients undergoing cardiac surgery.
Study context
- Population
- Patients awaiting elective cardiac surgery and procedures
- Participants
- 394 patients
- Comparison
- Multimodal personalised teleprehabilitation vs control
- Teleprehabilitationn = 197
- Controln = 197reference
- Primary endpoint
- MACE:
- CV death
- MI
- Stroke
- Hospitalization for HF or other life-threatening cardiac events
- Earlier or repeated intervention
- Follow-up
- From randomization until 1 year postoperatively
Methodological detailsmulticentre, blinded event adjudication
- Multicentre
- Blinded event adjudication
Primary result
As reported in the abstract
Difference
8.8%
95% CI 0.7%–16.8%
P = 0.032
Events by treatment group
Teleprehabilitationvs Control
difference 8.8% (95% CI 0.7%–16.8%); P = 0.032
Secondary outcomes
| Outcome | Adjusted OR (95% CI) | P value | |
|---|---|---|---|
| Primary endpoint, patients undergoing cardiac surgery (sensitivity analysis) | 0.54 (0.30–0.96) | P = 0.035 | |
| 0.20.5125Adjusted odds ratio (log scale) |
- Primary endpoint, patients undergoing cardiac surgery (sensitivity analysis): effect mainly in cardiac surgery rather than transcatheter procedures
Active smokers, elevated pulmonary risk scores, elevated depression scores
- Reduced with teleprehabilitation
Postoperative length of hospital stay, postoperative complications, physical fitness, obesity, malnutrition
- No significant difference
Original publication
The Effect of Teleprehabilitation on Adverse Events After Elective Cardiac Surgery: A Randomized Controlled Trial. J Am Coll Cardiol. Published 11 October 2024. doi:10.
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