Coronary disease & ACSTrial design
The European bifurcation club randomized trial of stepwise provisional stenting vs drug-coated balloon therapy for nonleft main true coronary bifurcations: The EBC drug-coated balloons (DCB) trial
- nonblinded, investigator-initiated, randomized control trial
- open-label
- multicenter
- international
Study context
- Population
- Patients with nonleft main true coronary bifurcations requiring revascularization, with significant atheroma in both main vessel and side branch; subacute (NSTEMI and unstable angina) and elective presentationsplanned recruitment
- Participants
- 750 patients
- Planned comparison
- DCB vs drug-eluting stents (DES) in the treatment of coronary artery bifurcation disease
- Primary endpoint
- Target Bifurcation Failure (composite of cardiovascular death, target bifurcation myocardial infarction, or target bifurcation revascularization)
- Follow-up
- 1 year
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
The European bifurcation club randomized trial of stepwise provisional stenting vs drug-coated balloon therapy for nonleft main true coronary bifurcations: The EBC DCB trial. Am Heart J. Published 29 April 2026. doi:10.1016/j.ahj.2026.107463
Summarised from the published abstract; every number is checked against it