Arrhythmias & electrophysiologyCohort study

The impact of modifiable risk factors in the association between socioeconomic status and sudden cardiac death in a prospective cohort study: equal access to healthcare, unequal outcome

Eur J Prev CardiolPublished

  • Prospective cohort study
  • mediation analysis

Authors' conclusion

We observed an inverse association between both income and education and the risk of SCD, which was only in part explained by common cardiac risk factors

Study context

Population
Participants in the Copenhagen City Heart Study, followed 1993–2016
Participants
10,006 participants · 822 sudden cardiac death (SCDs)
Exposure
Low vs high income and education level
Outcome
Incidence of SCD
Follow-up
24 years

Main finding

As reported in the abstract

SCD
Incidence rate ratio (95% CI)
Elementary school vs Long education
2.48(1.86–3.31)
Low income vs High income
2.34(1.85–2.96)

Observational data: associations, not effects.

Further findings

Mediation of education–SCD association by smoking, physical activity and BMI

Combined mediating effect, share of risk differences
∼20%

Original publication

The impact of modifiable risk factors in the association between socioeconomic status and sudden cardiac death in a prospective cohort study: equal access to healthcare, unequal outcome. Eur J Prev Cardiol. Published 21 March 2023. doi:10.1093/eurjpc/zwad086

Summarised from the published abstract; every number is checked against it