Heart failure & cardiomyopathies

The incremental role of late gadolinium enhancement in risk stratifying high risk patients with hypertrophic cardiomyopathy

Am Heart JPublished Retrospective cohort study

Authors' conclusion

LGE provides incremental prognostic value in refining risk stratification for SCD in HCM patients, especially when the decision for ICD placement may be clinical history alone.

Study context

Population
Hypertrophic cardiomyopathy (HCM) patients with CMR imaging and implanted implantable cardioverter-defibrillator (ICDs)
Participants
326 patients
Exposure
Late gadolinium enhancement (LGE) >15% vs lower LGE
Outcome
Appropriate ICD discharges
Methodological detailsmulti-site referral center
  • Multi-site referral center

Main finding

As reported in the abstract

Appropriate ICD discharge · study period
Participants with ≥1 appropriate ICD discharge
50

Observational data: associations, not effects.

Original publication

The incremental role of late gadolinium enhancement in risk stratifying high risk patients with hypertrophic cardiomyopathy. Am Heart J. Published 3 May 2025. doi:10.1016/j.ahj.2025.04.030

Composed by AI from the published abstract and checked against it. How Briefs are made →

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