Heart failure & cardiomyopathies
The incremental role of late gadolinium enhancement in risk stratifying high risk patients with hypertrophic cardiomyopathy
Authors' conclusion
LGE provides incremental prognostic value in refining risk stratification for SCD in HCM patients, especially when the decision for ICD placement may be clinical history alone.
Study context
- Population
- Hypertrophic cardiomyopathy (HCM) patients with CMR imaging and implanted implantable cardioverter-defibrillator (ICDs)
- Participants
- 326 patients
- Exposure
- Late gadolinium enhancement (LGE) >15% vs lower LGE
- Outcome
- Appropriate ICD discharges
Methodological detailsmulti-site referral center
- Multi-site referral center
Main finding
As reported in the abstract
Appropriate ICD discharge · study period
- Participants with ≥1 appropriate ICD discharge
- 50
Observational data: associations, not effects.
Original publication
The incremental role of late gadolinium enhancement in risk stratifying high risk patients with hypertrophic cardiomyopathy. Am Heart J. Published 3 May 2025. doi:10. 1016/ j. ahj. 2025. 04. 030
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