Arrhythmias & electrophysiology

The Misleading QRS Morphology of Scar-Related Ventricular Tachycardia

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

For scar-related VTs, the exit predicted from a vector-based QRS algorithm often differs from the location where ablation terminates the VT.

Study context

Population
Scar-related re-entrant LV ventricular tachycardia (VTs) (57.9% ischemic cardiomyopathy) with an identified region where radiofrequency ablation (RFA) terminated the VT
Participants
64 VTs
Outcome
Relation of the RFA termination site to the exit region predicted by a vector-based QRS algorithm (AHA 17-segment LV model)

Main finding

As reported in the abstract

QRS morphology discordant with termination region

Discordant VTs

57

89%

Termination region remote from circuit exit

22

34.4%

Termination site in circuit exit, but QRS suggested a different exit region

32

50%

Observational data: associations, not effects.

Further findings

Voltage maps and pace mapping

QRS vector often altered by scar

Original publication

The Misleading QRS Morphology of Scar-Related Ventricular Tachycardia. JACC Clin Electrophysiol. Published 28 August 2025. doi:10.1016/j.jacep.2025.07.004

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