Acute cardiac care & resuscitation
The Prevalence and Characteristics of Arrhythmic Mitral Valve Prolapse in Patients With Unexplained Cardiac Arrest
Authors' conclusion
MVP is associated with otherwise UCA (IVF), with a prevalence of 6.6%.
Study context
- Population
- Patients with unexplained cardiac arrest (no CAD, preserved LVEF, no apparent explanation on ECG)
- Participants
- 571 patients
- Exposure
- Idiopathic ventricular fibrillation (IVF) vs alternative diagnosis among patients with unexplained cardiac arrest (UCA)
- IVFn = 366
- Alternative diagnosisn = 205reference
- Outcome
- Prevalence and characteristics of MVP
Main finding
As reported in the abstract
Definite MVP prevalence
P = 0.03
- Any mitral valve prolapse (MVP) among all UCA
- 34 (6%)
Observational data: associations, not effects.
Further findings
| Outcome | Values | OR | P value |
|---|---|---|---|
| Bileaflet prolapse, AMVP vs nonarrhythmic MVP | AMVP 78% · Nonarrhythmic MVP 12.5% | 25.2 | P = 0.001 |
| Appropriate ICD therapies in AMVP · median follow-up 42 months | AMVP 21.1% |
- Bileaflet prolapse, AMVP vs nonarrhythmic MVP: 18 of 23 vs 1 of 8
- Appropriate ICD therapies in AMVP: 4 of 19
Original publication
The Prevalence and Characteristics of Arrhythmic Mitral Valve Prolapse in Patients With Unexplained Cardiac Arrest. JACC Clin Electrophysiol. Published 4 October 2023. doi:10.
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