Heart failure & cardiomyopathies
The Relation Between Socioeconomic Status and Invasive Haemodynamics at Evaluation for Advanced Heart Failure
Authors' conclusion
Most haemodynamic measurements were similar across layers of SES. Nevertheless, there were some indications of worse haemodynamics in patients with lower household income or a high accumulated burden of socioeconomic deprivation.
Study context
- Population
- Patients evaluated for advanced heart failure (HF) therapies
- Participants
- 631 patients
- Exposure
- Higher vs lower socioeconomic status (SES)
- Outcome
- Invasive haemodynamics (PCWP, CVP, cardiac index, PVR)
Methodological detailsconsecutive clinical registry linked to nationwide registries, adjusted for age and sex, Median age 53 years; 23% women
- Consecutive clinical registry linked to nationwide registries
- Adjusted for age and sex
- Median age 53 years; 23% women
Main finding
As reported in the abstract
Invasive haemodynamics (PCWP, CVP, cardiac index, PVR) by SES, adjusted for age and sex
- Increasing household income · per 100 000 Danish kroner
- Pulmonary capillary wedge pressure (PCWP) −0.18 mmHg (95% CI −0.36 to −0.01); P = 0.036
- Increasing household income · per 100 000 Danish kroner; not significant
- Central venous pressure (CVP) −0.07 mmHg (95% CI −0.21 to 0.06); P = 0.27
- Increasing household income · per 100 000 Danish kroner; not significant
- cardiac index −0.004 L/min/m² (95% CI −0.02 to 0.01); P = 0.60
- Increasing household income · per 100 000 Danish kroner; not significant
- Pulmonary vascular resistance (PVR) −0.003 Wood units (95% CI −0.37 to 0.16); P = 0.84
- Most deprived vs least deprived · higher
- adjusted mean PVR 0.35 Wood units (95% CI 0.02–0.68); P = 0.04
- Most deprived vs least deprived · similar
- PCWP 0.66 mmHg (95% CI −1.49 to 2.82); P = 0.55
- Most deprived vs least deprived · similar
- CVP −0.26 mmHg (95% CI −1.76 to 1.24); P = 0.73
- Most deprived vs least deprived · similar
- cardiac index −0.03 L/min/m² (95% CI −0.22 to 0.17); P = 0.78
Observational data: associations, not effects.
Further findings
Baseline characteristics, highest vs lowest income quartile
Male Q4 83% · Q1 67%
- Baseline characteristics, highest vs lowest income quartile: both P < 0.001
Original publication
The Relation Between Socioeconomic Status and Invasive Haemodynamics at Evaluation for Advanced Heart Failure. ESC Heart Fail. Published 30 September 2024. doi:10. 1002/ ehf2. 15089
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