Heart failure & cardiomyopathies

The Relation Between Socioeconomic Status and Invasive Haemodynamics at Evaluation for Advanced Heart Failure

ESC Heart FailPublished Cohort study

Authors' conclusion

Most haemodynamic measurements were similar across layers of SES. Nevertheless, there were some indications of worse haemodynamics in patients with lower household income or a high accumulated burden of socioeconomic deprivation.

Study context

Population
Patients evaluated for advanced heart failure (HF) therapies
Participants
631 patients
Exposure
Higher vs lower socioeconomic status (SES)
Outcome
Invasive haemodynamics (PCWP, CVP, cardiac index, PVR)
Methodological detailsconsecutive clinical registry linked to nationwide registries, adjusted for age and sex, Median age 53 years; 23% women
  • Consecutive clinical registry linked to nationwide registries
  • Adjusted for age and sex
  • Median age 53 years; 23% women

Main finding

As reported in the abstract

Invasive haemodynamics (PCWP, CVP, cardiac index, PVR) by SES, adjusted for age and sex
Increasing household income · per 100 000 Danish kroner
Pulmonary capillary wedge pressure (PCWP) −0.18 mmHg (95% CI −0.36 to −0.01); P = 0.036
Increasing household income · per 100 000 Danish kroner; not significant
Central venous pressure (CVP) −0.07 mmHg (95% CI −0.21 to 0.06); P = 0.27
Increasing household income · per 100 000 Danish kroner; not significant
cardiac index −0.004 L/min/m² (95% CI −0.02 to 0.01); P = 0.60
Increasing household income · per 100 000 Danish kroner; not significant
Pulmonary vascular resistance (PVR) −0.003 Wood units (95% CI −0.37 to 0.16); P = 0.84
Most deprived vs least deprived · higher
adjusted mean PVR 0.35 Wood units (95% CI 0.02–0.68); P = 0.04
Most deprived vs least deprived · similar
PCWP 0.66 mmHg (95% CI −1.49 to 2.82); P = 0.55
Most deprived vs least deprived · similar
CVP −0.26 mmHg (95% CI −1.76 to 1.24); P = 0.73
Most deprived vs least deprived · similar
cardiac index −0.03 L/min/m² (95% CI −0.22 to 0.17); P = 0.78

Observational data: associations, not effects.

Further findings

Baseline characteristics, highest vs lowest income quartile

Male Q4 83% · Q1 67%

  • Baseline characteristics, highest vs lowest income quartile: both P < 0.001

Original publication

The Relation Between Socioeconomic Status and Invasive Haemodynamics at Evaluation for Advanced Heart Failure. ESC Heart Fail. Published 30 September 2024. doi:10.1002/ehf2.15089

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