Prevention & lipidsDiagnostic or prognostic study
The relevance of competing risk adjustment in cardiovascular risk prediction models for clinical practice
- Prognostic model development study (cohort)
- Median follow-up 8.2 years (IQR 4.2-12.5)
Authors' conclusion
Individual predictions from the model unadjusted for competing risks were higher, reflecting the different interpretations of both models.
Study context
- Population
- Individuals with established atherosclerotic cardiovascular disease (CVD), UCC-SMART cohort
- Participants
- 8,355 individuals
- Comparison
- Fine and Gray model vs Cox model
- Outcome
- 10-year residual CVD risk prediction: calibration (predicted-observed ratio), discrimination and treatment eligibility
- Follow-up
- 10-year
Performance
As reported in the abstract
Treated at predicted risk > 20%
| Outcome | Fine and Gray model | Cox model |
|---|---|---|
| Predicted-observed ratio | Not reported in the abstract | 1.14 (95% CI 1.09-1.20) |
Original publication
The relevance of competing risk adjustment in cardiovascular risk prediction models for clinical practice. Eur J Prev Cardiol. Published 20 June 2023. doi:10.1093/eurjpc/zwad202
Summarised from the published abstract; every number is checked against it