Arrhythmias & electrophysiology
The Restitution Threshold Index Characterizes the Association Between Atrial Fibrillation Ventricular Rate and Ejection Fraction
Authors' conclusion
The RTI in persistent AF was associated with a reduced LVEF, whereas mean heart rate was not.
Study context
- Population
- Patients with persistent atrial fibrillation (AF) before catheter ablation
- Participants
- 104 patients
- Exposure
- Reduced left ventricular ejection fraction (LVEF) vs preserved LVEF
- Reduced LVEFn = 53
- Outcome
- Restitution threshold index (RTI: % burden of R-R intervals shorter than the restitution threshold) and its association with reduced LVEF and LVEF recovery after catheter ablation
Main finding
As reported in the abstract
RTI at an restitution threshold (RT) of 660 ms
P < 0.001
Observational data: associations, not effects.
Further findings
- Prediction of LVEF improvement after catheter ablation by restitution threshold index (RTI) (reduced LVEF)
- 0.74 (95% CI: 0.47-0.95) · AUC · PPV 0.97
- Prediction of LVEF improvement after catheter ablation by RTI (reduced LVEF) — LVEF improvement after catheter ablation (CA) in participants in sinus rhythm
- 39 of 47 (83.0%)
Original publication
The Restitution Threshold Index Characterizes the Association Between Atrial Fibrillation Ventricular Rate and Ejection Fraction. JACC Clin Electrophysiol. Published 11 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →