Heart failure & cardiomyopathies

The Role of Bioimpedance Analysis in Overweight and Obese Patients with Acute Heart Failure: A Pilot Study

ESC Heart FailPublished Randomised controlled trial

Authors' conclusion

Among overweight and obese patients with HF, BIA reduces NT-proBNP levels at 90 days compared with standard care. In addition, there is a trend towards lower incidence of AKI in the BIA-guided group.

Study context

Population
Overweight and obese patients admitted for acute heart failure (HF)
Participants
48 participants
Comparison
Bioelectrical impedance analysis (BIA)-guided management vs standard care
Primary endpoint
Severe AKI (serum creatinine increase >0.5 mg/dL)
Follow-up
During hospitalization
Methodological detailssingle-centre, single-blind
  • Single-centre
  • Single-blind

Primary result

As reported in the abstract

Severe AKI

Lower incidence of severe acute kidney injury (AKI) with BIA-guided, not significant

41.4% vs. 16.7%

Secondary outcomes

NT-proBNP < 1000 pg/mL (main secondary endpoint) · 90 days

P = 0.049

Safety

Adverse outcomes · 90 days

No differences in incidence of adverse outcomes

Original publication

The Role of Bioimpedance Analysis in Overweight and Obese Patients with Acute Heart Failure: A Pilot Study. ESC Heart Fail. Published 24 May 2023. doi:10.1002/ehf2.14398

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