Congenital heart diseaseCohort study
The SIDECAR 2.0 (S-ICD registry in European paediatric and young adult patients with congenital heart defects 2.0): an analysis of European S-ICD clinical practice and its evolution in paediatric patients
- Retrospective cohort study
- international
- multicentre
- observational registry
Authors' conclusion
This multicentre S-ICD European registry in paediatric and young patients demonstrated favourable outcomes, low IAS, and complication rates.
Study context
- Population
- Paediatric and young adult patients with congenital heart defects (CHD), cardiomyopathies, channelopathies or idiopathic VF, Europemean age 15 ± 3 years
- Participants
- 223 participants
- Outcome
- Safety and efficacy of subcutaneous implantable cardioverter-defibrillators (S-ICDs) (defibrillation efficacy, inappropriate and appropriate shocks, complications)
Main finding
As reported in the abstract
Defibrillation efficacy and appropriate shocks · median follow-up 28 (IQR: 12-55) months
Acute defibrillation success
100%
Patients with appropriate shocks
41 (18%)
Appropriate shock rate at 5 years
26%
First shock effective, discrete episodes
92%
Observational data: associations, not effects.
Further findings
Implantation technique
- Intermuscular implantation
- 65%
- Two-incision technique
- 88%
Safety
Intraoperative complications
- No intraoperative complications
Inappropriate shocks (IAS) and complications · 5 years
- IAS rate
- 20%
- Complication rate
- 5%
- Older age, intermuscular pocket and two-incision technique associated with fewer complications
Original publication
The SIDECAR 2.0 (S-ICD registry in European paediatric and young adult patients with congenital heart defects 2.0): an analysis of European S-ICD clinical practice and its evolution in paediatric patients. Europace. Published 30 October 2025. doi:10.1093/europace/euaf276
Summarised from the published abstract; every number is checked against it