Arrhythmias & electrophysiologyCohort study
The triggers of situational syncope do not influence the head-up tilt test response and prognosis
- Retrospective cohort study
- single-centre
- consecutive patients
Authors' conclusion
Situational syncope appears to be a homogenous syndrome, and different triggers do not impact the HUTT response or syncope recurrence at 1 year.
Study context
- Population
- Consecutive patients with situational syncope undergoing nitroglycerine (NTG)-potentiated head-up tilt test, Syncope Unit, 2017–2023
- Participants
- 236 patients
- Exposure
- Situational syncope stratified by trigger
- Micturitionn = 109
- Swallown = 32
- Defaecationn = 35
- Post-exercisen = 41
- Cough/sneezen = 17
- Outcome
- HUTT positivity rate, haemodynamic responses and syncope recurrence
- Follow-up
- 1 year
Main finding
As reported in the abstract
HUTT response and syncope recurrence by trigger
No statistically different syncope recurrence across triggers (Kaplan-Meier)
log-rank P = 0.21
Observational data: associations, not effects.
Original publication
The triggers of situational syncope do not influence the head-up tilt test response and prognosis. Europace. Published 6 August 2024. doi:10.1093/europace/euae208
Summarised from the published abstract; every number is checked against it