Congenital heart diseaseResearch article
Trans-Collateral Retrograde Perforation of the RVOT in Pulmonary Atresia/Ventricular Septal Defect: A Feasible Catheter-Based Approach
- study
Authors' conclusion
Retrograde trans-collateral right ventricular outflow tract perforation is a feasible and safe catheter-based strategy for selected patients with pulmonary atresia with ventricular septal defect, promoting central pulmonary artery growth and serving as a bridge to future surgical repair.
Study context
- Population
- Patients with pulmonary atresia and ventricular septal defect with major aortopulmonary collateral arteries dependent pulmonary circulation who underwent attempted retrograde trans-collateral right ventricular outflow tract perforation, October 2021 to February 2025including 1 unsuccessful procedure
- Participants
- 10 patients
Main finding
As reported in the abstract
Systemic oxygen saturation · Post-procedure
increased significantly
P <0.01
Further findings
Right and left pulmonary artery Z scores · Follow-up imaging
- significant improvements
- P < 0.01
Nakata index · Follow-up imaging
- median before
- 49
- median after
- 111.7 mm 2 /m 2
- significant increase
- P < 0.01
Baseline characteristics · at intervention
- median age
- 4.1 years
- median weight
- 17 kg
Original publication
Trans-Collateral Retrograde Perforation of the RVOT in Pulmonary Atresia/Ventricular Septal Defect: A Feasible Catheter-Based Approach. Circ Cardiovasc Interv. Published 5 February 2026. doi:10.1161/circinterventions.125.016002
Summarised from the published abstract; every number is checked against it