Valvular & structural heart disease
Transcatheter aortic valve implantation in pure aortic regurgitation: one-year outcomes of the AURORA trial
Authors' conclusion
The AURORA classification system shows that comprehensive anatomical assessment can lead to favourable outcomes in pure AR using conventional TAVI devices. The low pacemaker implantation rate and the absence of device failure in later cases suggest that optimal anatomical matching may be superior to aggressive oversizing strategies.
Study context
- Population
- Patients with severe pure aortic regurgitation (AR) and suitable anatomy (types 1–3 by the AURORA anatomical classification on multidetector computed tomography (CT)) undergoing transcatheter aortic valve implantation (TAVI) with the VitaFlow valve systemenrolled with suitable anatomy (types 1–3), of 187 screened patients
- Participants
- 100 patients
- Outcome
- Device success (primary efficacy endpoint)
Methodological detailsconducted across 16 centres in China
- Conducted across 16 centres in China
Main finding
As reported in the abstract
TAVI
91%
Observational data: associations, not effects.
Further findings
Baseline characteristics
- Mean age
- 72.7±7.2 years
- Mean Society of Thoracic Surgeons Predicted Risk of Mortality score
- 9.10±5.81%
Location of maximum contact forces on postprocedural CT
- Maximum contact forces primarily localised between the virtual annulus and the sinotubular junction (postprocedural CT analysis in 43 patients)
- 83.7% of cases
Device failure in later cases
- No device failure occurred in later cases
Safety
| Outcome | Values |
|---|---|
| New permanent pacemaker implantation | TAVI 9% |
Procedural mortality
- No procedural mortality
Original publication
Transcatheter aortic valve implantation in pure aortic regurgitation: one-year outcomes of the AURORA trial. EuroIntervention. Published 18 August 2025. doi:10.
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